ENPP2 anticorps (C-Term)
Aperçu rapide pour ENPP2 anticorps (C-Term) (ABIN2856278)
Antigène
Voir toutes ENPP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Humain, Souris
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Attributs du produit
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Rabbit Polyclonal antibody to Autotaxin (ectonucleotide pyrophosphatase/phosphodiesterase 2)
Autotaxin antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the C-terminus region of human Autotaxin. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Validation: Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.13 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." dans: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).
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: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." dans: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).
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- ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
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Autre désignation
- ectonucleotide pyrophosphatase/phosphodiesterase 2
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Sujet
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The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
Cellular Localization: Secreted -
Poids moléculaire
- 99 kDa
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ID gène
- 5168
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UniProt
- Q13822
Antigène
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